Lipid Composition for Lyophosome™ – Phosphatidylglycerol (PG)-based

Lipid Composition for LPG-514	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	10.00 mg/vial	12.55 umol	100

Lipid Composition for LPG-501	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	9.01	11.30	90
1,2-dioleoyl-sn-glycero-3-phosphocholine	0.99	1.26	10
Total	10.00 mg/vial	12.56 umol	100

Lipid Composition for LPG-502	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	8.02	10.06	80
1,2-dioleoyl-sn-glycero-3-phosphocholine	1.98	2.52	20
Total	10.00 mg/vial	12.58 umol	100

Lipid Composition for LPG-503	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	7.03	8.82	70
1,2-dioleoyl-sn-glycero-3-phosphocholine	2.97	3.78	30
Total	10.00 mg/vial	12.60 umol	100

Lipid Composition for LPG-504	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	6.03	7.57	60
1,2-dioleoyl-sn-glycero-3-phosphocholine	3.97	5.04	40
Total	10.00 mg/vial	12.61 umol	100

Lipid Composition for LPG-505	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	5.03	6.32	50
1,2-dioleoyl-sn-glycero-3-phosphocholine	4.97	6.32	50
Total	10.00 mg/vial	12.64 umol	100

Lipid Composition for LPG-506	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	4.03	5.06	40
1,2-dioleoyl-sn-glycero-3-phosphocholine	5.97	7.59	60
Total	10.00 mg/vial	12.65 umol	100

Lipid Composition for LPG-507	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	3.03	3.80	30
1,2-dioleoyl-sn-glycero-3-phosphocholine	6.97	8.87	70
Total	10.00 mg/vial	12.67 umol	100

Lipid Composition for LPG-508	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	2.02	2.54	20
1,2-dioleoyl-sn-glycero-3-phosphocholine	7.98	10.15	80
Total	10.00 mg/vial	12.69 umol	100

Lipid Composition for LPG-509	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	1.01	1.27	10
1,2-dioleoyl-sn-glycero-3-phosphocholine	8.99	11.43	90
Total	10.00 mg/vial	12.70 umol	100

Lipid Composition for LPG-510	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	0.51	0.64	5
1,2-dioleoyl-sn-glycero-3-phosphocholine	9.49	12.07	95
Total	10.00 mg/vial	12.71 umol	100

Lipid Composition for LPG-511	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	0.20	0.25	2
1,2-dioleoyl-sn-glycero-3-phosphocholine	9.80	12.47	98
Total	10.00 mg/vial	12.72 umol	100

Lipid Composition for LPG-512	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	0.10	0.13	1
1,2-dioleoyl-sn-glycero-3-phosphocholine	9.90	12.59	99
Total	10.00 mg/vial	12.72 umol	100

Lipid Composition for LPG-513	Amount (mg/vial)	Amount (umol)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)	0.05	0.06	0.5
1,2-dioleoyl-sn-glycero-3-phosphocholine	9.95	12.66	99.5
Total	10.00 mg/vial	12.72 umol	100