| Lipid Composition for CDP-501 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 3.49 | 5 | 50 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 3.93 | 5 | 50 |
| Total | 7.42 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-502 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 2.79 | 4 | 40 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 4.72 | 6 | 60 |
| Total | 7.51 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-503 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 2.10 | 3 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 5.50 | 7 | 70 |
| Total | 7.60 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-504 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 1.40 | 2 | 20 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 6.29 | 8 | 80 |
| Total | 7.69 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-505 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 0.699 | 1 | 10 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 7.08 | 9 | 90 |
| Total | 7.77 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-506 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 0.349 | 0.5 | 5 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 7.47 | 9.5 | 95 |
| Total | 7.82 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-507 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 0.14 | 0.2 | 2 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 7.70 | 9.8 | 98 |
| Total | 7.84 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-508 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 0.0699 | 0.1 | 1 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 7.78 | 9.9 | 99 |
| Total | 7.85 mg/ml | 10 mM | 100 |
| Lipid Composition for CDP-509 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) (DOTAP) | 0.0349 | 0.05 | 0.5 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) | 7.82 | 9.95 | 99.5 |
| Totoal | 7.86 mg/ml | 10 mM | 100 |
