| Lipid Composition for CAR-201 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 14.9 | 10 | 100 |
| Lipid Composition for CAR-202 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1',3'-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol (sodium salt) (TOCL) | 15 | 10 | 100 |
| Lipid Composition for CAR-203 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| 1',3'-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-sn-glycerol (sodium salt) (TMCL) | 12.8 | 10 | 100 |
| Lipid Composition for CAR-204 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 6.98 | 9 | 90 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 1.49 | 1 | 10 |
| Total | 8.47 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-205 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 6.59 | 8.5 | 85 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 2.24 | 1.5 | 15 |
| Total | 8.83 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-206 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 6.20 | 8 | 80 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 2.99 | 2 | 20 |
| Total | 9.19 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-207 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 5.43 | 7 | 70 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 4.48 | 3 | 30 |
| Total | 9.91 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-208 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 4.65 | 6 | 60 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 5.98 | 4 | 40 |
| Total | 10.63 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-209 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 3.88 | 5 | 50 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 7.47 | 5 | 50 |
| Total | 11.35 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-210 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 3.10 | 4 | 40 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 8.97 | 6 | 60 |
| Total | 12.07 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-211 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 2.33 | 3 | 30 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 10.46 | 7 | 70 |
| Total | 12.79 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-212 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 1.55 | 2 | 20 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 11.95 | 8 | 80 |
| Total | 13.50 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-213 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 0.775 | 1 | 10 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 13.45 | 9 | 90 |
| Total | 14.23 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-214 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 0.39 | 0.5 | 5 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 14.19 | 9.5 | 95 |
| Total | 14.58 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-215 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 0.16 | 0.2 | 2 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 14.64 | 9.8 | 98 |
| Total | 14.80 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-216 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 0.08 | 0.1 | 1 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 14.79 | 9.9 | 99 |
| Total | 14.87 mg/ml | 10 mM | 100 |
| Lipid Composition for CAR-217 | Concentration (mg/ml) | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|---|
| L-alpha-phosphatidylcholine | 0.04 | 0.05 | 0.5 |
| Cardiolipin (CL) (extracted from bovine heart) (sodium salt) | 14.87 | 9.95 | 99.5 |
| Total | 14.91 mg/ml | 10 mM | 100 |
