Lipid Composition for Cellsome® – Phosphatidylglycerol (PG)-based

Lipid Composition for CPG-514	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	7.97	10	100

Lipid Composition for CPG-501	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	7.17	9	90
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	0.786	1	10
Total	7.96 mg/ml	10 mM	100

Lipid Composition for CPG-502	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	6.38	8	80
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	1.57	2	20
Total	7.95 mg/ml	10 mM	100

Lipid Composition for CPG-503	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	5.58	7	70
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	2.36	3	30
Total	7.94 mg/ml	10 mM	100

Lipid Composition for CPG-504	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	4.78	6	60
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	3.14	4	40
Total	7.93 mg/ml	10 mM	100

Lipid Composition for CPG-505	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	3.99	5	50
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	3.93	5	50
Total	7.92 mg/ml	10 mM	100

Lipid Composition for CPG-506	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	3.19	4	40
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	4.72	6	60
Total	7.91 mg/ml	10 mM	100

Lipid Composition for CPG-507	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	2.39	3	30
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	5.50	7	70
Total	7.89 mg/ml	10 mM	100

Lipid Composition for CPG-508	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	1.59	2	20
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	6.29	8	80
Total	7.88 mg/ml	10 mM	100

Lipid Composition for CPG-509	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	0.797	1	10
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	7.08	9	90
Total	7.877 mg/ml	10 mM	100

Lipid Composition for CPG-510	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	0.399	0.5	5
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	7.47	9.5	95
Total	7.87 mg/ml	10 mM	100

Lipid Composition for CPG-511	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	0.159	0.2	2
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	7.70	9.8	98
Total	7.86 mg/ml	10 mM	100

Lipid Composition for CPG-512	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	0.0797	0.1	1
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	7.78	9.9	99
Total	7.86 mg/ml	10 mM	100

Lipid Composition for CPG-513	Concentration (mg/ml)	Concentration (mM)	Molar Ratio Percentage
1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (DOPG)	0.0399	0.05	0.5
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)	7.82	9.95	99.5
Total	7.86 mg/ml	10 mM	100