| Lipid Composition for GEN-7020 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 100 |
| Lipid Composition for GEN-7018 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 50 |
| Cholesterol | 2 | 50 |
| Lipid Composition for GEN-7019 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 50 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) | 2 | 50 |
| Lipid Composition for GEN-7026 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 99.5 |
| 1,1'-dioctadecyl-3,3,3',3'-etramethylindocarbocyanine perchlorate (DiI) | 0.002 | 0.5 |
| Lipid Composition for GEN-7025 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 99.5 |
| 3,3'-dilinoleyloxacarbocyanine perchlorate (DiO) | 0.01 | 0.5 |
| Lipid Composition for GEN-7021 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 49.75 |
| Cholesterol | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2- 1,3-benzoxadiazol-4-yl) (ammonium salt) (NBD-DOPE) | 0.02 | 0.5 |
| Lipid Composition for GEN-7022 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 49.75 |
| Cholesterol | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) (ammonium salt) (Rhod-PE) | 0.02 | 0.5 |
| Lipid Composition for GEN-7023 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2- 1,3-benzoxadiazol-4-yl) (ammonium salt) (NBD-DOPE) | 0.02 | 0.5 |
| Lipid Composition for GEN-7024 | Concentration (mM) | Molar Ratio Percentage |
|---|---|---|
| 1,2-di-O-octadecenyl-3-trimethylammonium propane (chloride salt) (DOTMA) | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) | 2 | 49.75 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) (ammonium salt) (Rhod-PE) | 0.02 | 0.5 |
