| Lipid Composition for ADPG-201 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.975 | 0.68 | 65 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.06 mg/vial | 100 |
| Lipid Composition for ADPG-202 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.900 | 0.63 | 60 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.075 | 0.06 | 5 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.07 mg/vial | 100 |
| Lipid Composition for ADPG-203 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.750 | 0.52 | 50 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.225 | 0.18 | 15 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.08 mg/vial | 100 |
| Lipid Composition for ADPG-204 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.600 | 0.42 | 40 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.375 | 0.29 | 25 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.09 mg/vial | 100 |
| Lipid Composition for ADPG-205 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.450 | 0.31 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.525 | 0.41 | 35 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.10 mg/vial | 100 |
| Lipid Composition for ADPG-206 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.300 | 0.21 | 20 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.675 | 0.53 | 45 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.12 mg/vial | 100 |
| Lipid Composition for ADPG-207 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.150 | 0.10 | 10 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.825 | 0.65 | 55 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | µmol/vial | 1.13 mg/vial | 100 |
| Lipid Composition for ADPG-208 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.075 | 0.05 | 5 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.900 | 0.71 | 60 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.14 mg/vial | 100 |
| Lipid Composition for ADPG-209 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.0375 | 0.03 | 2.5 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.9375 | 0.74 | 62.5 |
| Cholesterol | 0.4500 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.0750 | 0.21 | 5 |
| Total | 1.5000 µmol/vial | 1.15 mg/vial | 100 |
| Lipid Composition for ADPG-210 | Amount (µmol/vial) | Amount (mg/vial) | Molar Ratio Percentage |
|---|---|---|---|
| 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt) | 0.015 | 0.01 | 1 |
| 1,2-dioleoyl-sn-glycero-3-phosphocholine | 0.960 | 0.75 | 64 |
| Cholesterol | 0.450 | 0.17 | 30 |
| 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt) | 0.075 | 0.21 | 5 |
| Total | 1.500 µmol/vial | 1.14 mg/vial | 100 |
